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Dynamic Analysis of Proviral Induction and De Novo Methylation: Implications for a Histone Deacetylase-Independent, Methylation Density-Dependent Mechanism of Transcriptional Repression

Methylation of cytosines in the CpG dinucleotide is generally associated with transcriptional repression in mammalian cells, and recent findings implicate histone deacetylation in methylation-mediated repression. Analyses of histone acetylation in in vitro-methylated transfected plasmids support thi...

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Bibliografische gegevens
Hoofdauteurs: Lorincz, Matthew C., Schübeler, Dirk, Goeke, Scott C., Walters, Mark, Groudine, Mark, Martin, David I. K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85201/
https://ncbi.nlm.nih.gov/pubmed/10629041
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