A Cell Cycle-Specific Requirement for the XRCC1 BRCT II Domain during Mammalian DNA Strand Break Repair

XRCC1 protein is essential for viability in mammals and is required for efficient DNA single-strand break repair and genetic stability following DNA base damage. We report here that XRCC1-dependent strand break repair in G(1) phase of the cell cycle is abolished by mutations created within the XRCC1...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Taylor, Richard M., Moore, David J., Whitehouse, Jenna, Johnson, Penny, Caldecott, Keith W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.735-740.2000
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