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Integration of Calcium and Cyclic AMP Signaling Pathways by 14-3-3

Calcium-stimulated nuclear factor of activated T cells (NFAT) transcription activity at the interleukin-2 promoter is negatively regulated by cyclic AMP (cAMP). This effect of cAMP is mediated, in part, by protein kinase A phosphorylation of NFAT. The mechanism of regulation involves the creation of...

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Bibliografiske detaljer
Main Authors: Chow, Chi-Wing, Davis, Roger J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85175/
https://ncbi.nlm.nih.gov/pubmed/10611249
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