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Distinct Variants of Helicobacter pylori cagA Are Associated with vacA Subtypes

The diversity of the cytotoxin-associated gene (cagA) of Helicobacter pylori was analyzed in 45 isolates obtained from nine countries. We examined variation in the 5′ end of the cagA open reading frame as determined by PCR and sequencing. Phylogenetic analysis revealed the existence of at least two...

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Bibliographic Details
Main Authors: van Doorn, Leen-Jan, Figueiredo, Céu, Sanna, Ricardo, Blaser, Martin J., Quint, Wim G. V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85143/
https://ncbi.nlm.nih.gov/pubmed/10364602
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