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Distinct Variants of Helicobacter pylori cagA Are Associated with vacA Subtypes

The diversity of the cytotoxin-associated gene (cagA) of Helicobacter pylori was analyzed in 45 isolates obtained from nine countries. We examined variation in the 5′ end of the cagA open reading frame as determined by PCR and sequencing. Phylogenetic analysis revealed the existence of at least two...

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Autors principals: van Doorn, Leen-Jan, Figueiredo, Céu, Sanna, Ricardo, Blaser, Martin J., Quint, Wim G. V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85143/
https://ncbi.nlm.nih.gov/pubmed/10364602
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