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c-Jun-Dependent CD95-L Expression Is a Rate-Limiting Step in the Induction of Apoptosis by Alkylating Agents

Mouse 3T3 fibroblasts derived from fetuses lacking c-Jun were used to define an essential role of c-Jun, a main component of the transcription factor AP-1, in the cellular response to the alkylating agent methyl methanesulfonate (MMS). MMS represents the most potent and selective activator of the st...

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Autors principals: Kolbus, Andrea, Herr, Ingrid, Schreiber, Martin, Debatin, Klaus-Michael, Wagner, Erwin F., Angel, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85135/
https://ncbi.nlm.nih.gov/pubmed/10611236
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