INK4d-Deficient Mice Are Fertile Despite Testicular Atrophy

The INK4 family of cyclin-dependent kinase (CDK) inhibitors includes four 15- to 19-kDa polypeptides (p16(INK4a), p15(INK4b), p18(INK4c), and p19(INK4d)) that bind to CDK4 and CDK6. By disrupting cyclin D-dependent holoenzymes, INK4 proteins prevent phosphorylation of the retinoblastoma protein and...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Zindy, Frederique, van Deursen, Jan, Grosveld, Gerard, Sherr, Charles J., Roussel, Martine F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2000
Fag:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594039/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.372-378.2000
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