The G-Protein β Subunit GPB1 Is Required for Mating and Haploid Fruiting in Cryptococcus neoformans

Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle. The gene encoding a heterotrimeric G-protein β subunit, GPB1, was cloned and disrupted. gpb1 mutant strains are sterile, indicating a role for this gene in mating. GPB1 plays an active role in mediating response...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Wang, Ping, Perfect, John R., Heitman, Joseph
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.352-362.2000
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