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The G-Protein β Subunit GPB1 Is Required for Mating and Haploid Fruiting in Cryptococcus neoformans

Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle. The gene encoding a heterotrimeric G-protein β subunit, GPB1, was cloned and disrupted. gpb1 mutant strains are sterile, indicating a role for this gene in mating. GPB1 plays an active role in mediating response...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Ping, Perfect, John R., Heitman, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85090/
https://ncbi.nlm.nih.gov/pubmed/10594037
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