Essential Function of the Polo Box of Cdc5 in Subcellular Localization and Induction of Cytokinetic Structures

Members of the polo subfamily of protein kinases play pivotal roles in cell proliferation. In addition to the kinase domain, polo kinases have a strikingly conserved sequence in the noncatalytic C-terminal domain, termed the polo box. Here we show that the budding-yeast polo kinase Cdc5, when fused...

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Bibliographic Details
Main Authors: Song, Sukgil, Grenfell, Tallessyn Z., Garfield, Susan, Erikson, Raymond L., Lee, Kyung S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85084/
https://ncbi.nlm.nih.gov/pubmed/10594031
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