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ei24, a p53 Response Gene Involved in Growth Suppression and Apoptosis

DNA damage and/or hyperproliferative signals activate the wild-type p53 tumor suppressor protein, which induces a G(1) cell cycle arrest or apoptosis. Although the mechanism of p53-mediated cell cycle arrest is fairly well defined, the p53-dependent pathway regulating apoptosis is poorly understood....

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Autori principali: Gu, Zhengming, Flemington, Cathy, Chittenden, Thomas, Zambetti, Gerard P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC85079/
https://ncbi.nlm.nih.gov/pubmed/10594026
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