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Hsp90 Binds and Regulates the Ligand-Inducible α Subunit of Eukaryotic Translation Initiation Factor Kinase Gcn2

The protein kinase Gcn2 stimulates translation of the yeast transcription factor Gcn4 upon amino acid starvation. Using genetic and biochemical approaches, we show that Gcn2 is regulated by the molecular chaperone Hsp90 in budding yeast Saccharomyces cerevisiae. Specifically, we found that (i) sever...

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Bibliografski detalji
Glavni autori: Donzé, Olivier, Picard, Didier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84941/
https://ncbi.nlm.nih.gov/pubmed/10567567
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