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Hsp90 Binds and Regulates the Ligand-Inducible α Subunit of Eukaryotic Translation Initiation Factor Kinase Gcn2

The protein kinase Gcn2 stimulates translation of the yeast transcription factor Gcn4 upon amino acid starvation. Using genetic and biochemical approaches, we show that Gcn2 is regulated by the molecular chaperone Hsp90 in budding yeast Saccharomyces cerevisiae. Specifically, we found that (i) sever...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Donzé, Olivier, Picard, Didier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8422
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