Pbx-Hox Heterodimers Recruit Coactivator-Corepressor Complexes in an Isoform-Specific Manner

Homeobox (hox) proteins have been shown to regulate cell fate and segment identity by promoting the expression of specific genetic programs. In contrast to their restricted biological action in vivo, however, most homeodomain factors exhibit promiscuous DNA binding properties in vitro, suggesting a...

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Main Authors: Asahara, Hiroshi, Dutta, Sanjoy, Kao, Hung-Ying, Evans, Ronald M., Montminy, Marc
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC84906/
https://ncbi.nlm.nih.gov/pubmed/10567547
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