Biochemical Analysis of Distinct Activation Functions in p300 That Enhance Transcription Initiation with Chromatin Templates

To investigate the mechanisms of transcriptional enhancement by the p300 coactivator, we analyzed wild-type and mutant versions of p300 with a chromatin transcription system in vitro. Estrogen receptor, NF-κB p65 plus Sp1, and Gal4-VP16 were used as different sequence-specific activators. The CH3 do...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Kraus, W. Lee, Manning, E. Tory, Kadonaga, James T.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8123
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