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Biological and Regulatory Properties of Vav-3, a New Member of the Vav Family of Oncoproteins

We report here the identification and characterization of a novel Vav family member, Vav-3. Signaling experiments demonstrate that Vav-3 participates in pathways activated by protein tyrosine kinases. Vav-3 promotes the exchange of nucleotides on RhoA, on RhoG and, to a lesser extent, on Rac-1. Duri...

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Detalles Bibliográficos
Main Authors: Movilla, Nieves, Bustelo, Xosé R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84867/
https://ncbi.nlm.nih.gov/pubmed/10523675
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