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Biological and Regulatory Properties of Vav-3, a New Member of the Vav Family of Oncoproteins

We report here the identification and characterization of a novel Vav family member, Vav-3. Signaling experiments demonstrate that Vav-3 participates in pathways activated by protein tyrosine kinases. Vav-3 promotes the exchange of nucleotides on RhoA, on RhoG and, to a lesser extent, on Rac-1. Duri...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Movilla, Nieves, Bustelo, Xosé R.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7870
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