Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation

Dbs was identified initially as a transforming protein and is a member of the Dbl family of proteins (>20 mammalian members). Here we show that Dbs, like its rat homolog Ost and the closely related Dbl, exhibited guanine nucleotide exchange activity for the Rho family members RhoA and Cdc42, but...

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Autori principali: Whitehead, Ian P., Lambert, Que T., Glaven, Judith A., Abe, Karon, Rossman, Kent L., Mahon, Gwendolyn M., Trzaskos, James M., Kay, Robert, Campbell, Sharon L., Der, Channing J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC84831/
https://ncbi.nlm.nih.gov/pubmed/10523665
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