Antagonistic Effects of Protein Kinase C α and δ on Both Transformation and Phospholipase D Activity Mediated by the Epidermal Growth Factor Receptor

Downregulation of protein kinase C δ (PKC δ) by treatment with the tumor-promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) transforms cells that overexpress the non-receptor class tyrosine kinase c-Src (Z. Lu et al., Mol. Cell. Biol. 17:3418–3428, 1997). We extended these studies to...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Hornia, Armand, Lu, Zhimin, Sukezane, Taiko, Zhong, Minghao, Joseph, Troy, Frankel, Paul, Foster, David A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7672
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