Elevated Phospholipase D Activity in H-Ras- but Not K-Ras-Transformed Cells by the Synergistic Action of RalA and ARF6

Phospholipase D (PLD) activity is elevated in response to the oncogenic stimulus of H-Ras but not K-Ras. H-Ras and K-Ras have been reported to localize to different membrane microdomains, with H-Ras localizing to caveolin-enriched light membrane fractions. We reported previously that PLD activity el...

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Autors principals: Xu, Lizhong, Frankel, Paul, Jackson, Desmond, Rotunda, Thuy, Boshans, Rita L., D'Souza-Schorey, Crislyn, Foster, David A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151535/
https://ncbi.nlm.nih.gov/pubmed/12509462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.645-654.2003
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