Multiple Cbfa/AML Sites in the Rat Osteocalcin Promoter Are Required for Basal and Vitamin D-Responsive Transcription and Contribute to Chromatin Organization

Three Cbfa motifs are strategically positioned in the bone-specific rat osteocalcin (rOC) promoter. Sites A and B flank the vitamin D response element in the distal promoter and sites B and C flank a positioned nucleosome in the proximal promoter. The functional significance of each Cbfa element was...

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Publicat a:	Mol Cell Biol
Autors principals:	Javed, Amjad, Gutierrez, Soraya, Montecino, Martin, van Wijnen, André J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1999
Matèries:	Transcriptional Regulation
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7491
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