A Region within the RAP74 Subunit of Human Transcription Factor IIF Is Critical for Initiation but Dispensable for Complex Assembly

Human transcription factor IIF (TFIIF) is an α(2)β(2) heterotetramer of RNA polymerase II-associating 74 (RAP74) and RAP30 subunits. Mutagenic analysis shows that the N-terminal region of RAP74 between L155 (leucine at codon 155) and M177 is important for initiation. Mutants in this region have redu...

Description complète

Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Ren, Delin, Lei, Lei, Burton, Zachary F.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7377
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!