A Region within the RAP74 Subunit of Human Transcription Factor IIF Is Critical for Initiation but Dispensable for Complex Assembly

Human transcription factor IIF (TFIIF) is an α(2)β(2) heterotetramer of RNA polymerase II-associating 74 (RAP74) and RAP30 subunits. Mutagenic analysis shows that the N-terminal region of RAP74 between L155 (leucine at codon 155) and M177 is important for initiation. Mutants in this region have redu...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ren, Delin, Lei, Lei, Burton, Zachary F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7377
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