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Transcriptional Repression of Stat6-Dependent Interleukin-4-Induced Genes by BCL-6: Specific Regulation of Iɛ Transcription and Immunoglobulin E Switching

The BCL-6 proto-oncogene encodes a POZ/zinc-finger transcription factor that is expressed in B cells and a subset of CD4(+) T cells within germinal centers. Recent evidence suggests that BCL-6 can act as a sequence-specific repressor of transcription, but the target genes for this activity have not...

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Publicado no:Mol Cell Biol
Principais autores: Harris, Miera B., Chang, Chih-Chao, Berton, Michael T., Danial, Nika N., Zhang, Jandong, Kuehner, Denise, Ye, Bihui H., Kvatyuk, Marina, Pandolfi, Pier Paolo, Cattoretti, Giorgio, Dalla-Favera, Riccardo, Rothman, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1999
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84719/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.7264
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