Leukemic HRX Fusion Proteins Inhibit GADD34-Induced Apoptosis and Associate with the GADD34 and hSNF5/INI1 Proteins

One of the most common chromosomal abnormalities in acute leukemia is a reciprocal translocation involving the HRX gene (also called MLL, ALL-1, or HTRX) at chromosomal locus 11q23, resulting in the formation of HRX fusion proteins. Using the yeast two-hybrid system and human cell culture coimmunopr...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Adler, Haskell T., Chinery, Rebecca, Wu, Daniel Y., Kussick, Steven J., Payne, John M., Fornace, Albert J., Tkachuk, Douglas C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1999
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.7050
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