Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in Saccharomyces cerevisiae

Rsp5 is an E3 ubiquitin-protein ligase of Saccharomyces cerevisiae that belongs to the hect domain family of E3 proteins. We have previously shown that Rsp5 binds and ubiquitinates the largest subunit of RNA polymerase II, Rpb1, in vitro. We show here that Rpb1 ubiquitination and degradation are ind...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Beaudenon, Sylvie L., Huacani, Maria R., Wang, Guangli, McDonnell, Donald P., Huibregtse, Jon M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6972
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