Cytomegalovirus IE2 Protein Stimulates Interleukin 1β Gene Transcription via Tethering to Spi-1/PU.1

Potent induction of the gene coding for human prointerleukin 1β (il1b) normally requires a far-upstream inducible enhancer in addition to a minimal promoter located between positions −131 and +12. The transcription factor Spi-1 (also called PU.1) is necessary for expression and binds to the minimal...

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Main Authors: Wara-aswapati, Nawarat, Yang, Zhiyong, Waterman, Wayne R., Koyama, Yoshinobu, Tetradis, Sotirios, Choy, Bob K., Webb, Andrew C., Auron, Philip E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC84677/
https://ncbi.nlm.nih.gov/pubmed/10490619
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