The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction.

In these studies, we have identified DNA sequences and specific protein interactions necessary for transcriptional regulation of the human prointerleukin 1 beta (proIL-1 beta) gene. A cell-type-independent lipopolysaccharide (LPS)-responsive enhancer element located between -3757 and -2729 bp upstre...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Shirakawa, F, Saito, K, Bonagura, C A, Galson, D L, Fenton, M J, Webb, A C, Auron, P E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359442/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1332-1344.1993
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