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The Acidic Domain and First Immunoglobulin-Like Loop of Fibroblast Growth Factor Receptor 2 Modulate Downstream Signaling through Glycosaminoglycan Modification

Fibroblast growth factor receptors (FGFRs) are membrane-spanning tyrosine kinases that have been implicated in a variety of biological processes including mitogenesis, cell migration, development, and differentiation. We identified a unique isoform of FGFR2 expressed as a diffuse band with an unusua...

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Bibliographic Details
Main Authors: Sakaguchi, Kazushige, Lorenzi, Matthew V., Bottaro, Donald P., Miki, Toru
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84670/
https://ncbi.nlm.nih.gov/pubmed/10490614
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