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Roles of Cell Division and Gene Transcription in the Methylation of CpG Islands

De novo methylation of CpG islands within the promoters of eukaryotic genes is often associated with their transcriptional repression, yet the methylation of CpG islands located downstream of promoters does not block transcription. We investigated the kinetics of mRNA induction, demethylation, and r...

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Detalhes bibliográficos
Main Authors: Bender, Christina M., Gonzalgo, Mark L., Gonzales, Felicidad A., Nguyen, Carvell T., Robertson, Keith D., Jones, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84656/
https://ncbi.nlm.nih.gov/pubmed/10490608
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