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RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins

Retinoblastoma (RB) tumor suppressor family proteins block cell proliferation in part by repressing certain E2F-specific promoters. Both histone deacetylase (HDAC)-dependent and -independent repression activities are associated with the RB “pocket.” The mechanism by which these two repression functi...

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Udgivet i:Mol Cell Biol
Principais autores: Lai, Albert, Lee, Joseph M., Yang, Wen-Ming, DeCaprio, James A., Kaelin, William G., Seto, Edward, Branton, Philip E.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6632
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