RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins

Retinoblastoma (RB) tumor suppressor family proteins block cell proliferation in part by repressing certain E2F-specific promoters. Both histone deacetylase (HDAC)-dependent and -independent repression activities are associated with the RB “pocket.” The mechanism by which these two repression functi...

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Main Authors: Lai, Albert, Lee, Joseph M., Yang, Wen-Ming, DeCaprio, James A., Kaelin, William G., Seto, Edward, Branton, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Transcriptional Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84642/
https://ncbi.nlm.nih.gov/pubmed/10490602
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