Loading...

The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2

V(D)J recombination is initiated by the specific binding of the RAG1-RAG2 (RAG1/2) complex to the heptamer-nonamer recombination signal sequences (RSS). Several steps of the V(D)J recombination reaction can be reconstituted in vitro with only RAG1/2 plus the high-mobility-group protein HMG1 or HMG2....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Aidinis, Vassilis, Bonaldi, Tiziana, Beltrame, Monica, Santagata, Sandro, Bianchi, Marco E., Spanopoulou, Eugenia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84623/
https://ncbi.nlm.nih.gov/pubmed/10490593
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!