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The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2

V(D)J recombination is initiated by the specific binding of the RAG1-RAG2 (RAG1/2) complex to the heptamer-nonamer recombination signal sequences (RSS). Several steps of the V(D)J recombination reaction can be reconstituted in vitro with only RAG1/2 plus the high-mobility-group protein HMG1 or HMG2....

詳細記述

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書誌詳細
主要な著者: Aidinis, Vassilis, Bonaldi, Tiziana, Beltrame, Monica, Santagata, Sandro, Bianchi, Marco E., Spanopoulou, Eugenia
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC84623/
https://ncbi.nlm.nih.gov/pubmed/10490593
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