Insulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt

Cyclic nucleotide phosphodiesterase (PDE) is an important regulator of the cellular concentrations of the second messengers cyclic AMP (cAMP) and cGMP. Insulin activates the 3B isoform of PDE in adipocytes in a phosphoinositide 3-kinase-dependent manner; however, downstream effectors that mediate si...

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Bibliografiske detaljer
Main Authors: Kitamura, Tadahiro, Kitamura, Yukari, Kuroda, Shoji, Hino, Yasuhisa, Ando, Miwa, Kotani, Ko, Konishi, Hiroaki, Matsuzaki, Hidenori, Kikkawa, Ushio, Ogawa, Wataru, Kasuga, Masato
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84592/
https://ncbi.nlm.nih.gov/pubmed/10454575
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