Insulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt

Cyclic nucleotide phosphodiesterase (PDE) is an important regulator of the cellular concentrations of the second messengers cyclic AMP (cAMP) and cGMP. Insulin activates the 3B isoform of PDE in adipocytes in a phosphoinositide 3-kinase-dependent manner; however, downstream effectors that mediate si...

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Autors principals: Kitamura, Tadahiro, Kitamura, Yukari, Kuroda, Shoji, Hino, Yasuhisa, Ando, Miwa, Kotani, Ko, Konishi, Hiroaki, Matsuzaki, Hidenori, Kikkawa, Ushio, Ogawa, Wataru, Kasuga, Masato
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84592/
https://ncbi.nlm.nih.gov/pubmed/10454575
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