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Interactions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae

In the yeast Saccharomyces cerevisiae, chromosomes terminate with a repetitive sequence [poly(TG(1–3))] 350 to 500 bp in length. Strains with a mutation of TEL1, a homolog of the human gene (ATM) mutated in patients with ataxia telangiectasia, have short but stable telomeric repeats. Mutations of TL...

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Détails bibliographiques
Auteurs principaux: Ritchie, Kim B., Mallory, Julia C., Petes, Thomas D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84515/
https://ncbi.nlm.nih.gov/pubmed/10454554
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