Interactions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae

In the yeast Saccharomyces cerevisiae, chromosomes terminate with a repetitive sequence [poly(TG(1–3))] 350 to 500 bp in length. Strains with a mutation of TEL1, a homolog of the human gene (ATM) mutated in patients with ataxia telangiectasia, have short but stable telomeric repeats. Mutations of TL...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ritchie, Kim B., Mallory, Julia C., Petes, Thomas D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6065
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