Overproduction of Human Myt1 Kinase Induces a G(2) Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes

The Myt1 protein kinase functions to negatively regulate Cdc2-cyclin B complexes by phosphorylating Cdc2 on threonine 14 and tyrosine 15. Throughout interphase, human Myt1 localizes to the endoplasmic reticulum and Golgi complex, whereas Cdc2-cyclin B1 complexes shuttle between the nucleus and the c...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Liu, Feng, Rothblum-Oviatt, Cynthia, Ryan, Christine E., Piwnica-Worms, Helen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.5113
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