Overproduction of Human Myt1 Kinase Induces a G(2) Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes
The Myt1 protein kinase functions to negatively regulate Cdc2-cyclin B complexes by phosphorylating Cdc2 on threonine 14 and tyrosine 15. Throughout interphase, human Myt1 localizes to the endoplasmic reticulum and Golgi complex, whereas Cdc2-cyclin B1 complexes shuttle between the nucleus and the c...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.5113 |
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