Cell Cycle Withdrawal Promotes Myogenic Induction of Akt, a Positive Modulator of Myocyte Survival

During myogenesis, proliferating myoblasts withdraw from the cell cycle, acquire an apoptosis-resistant phenotype, and differentiate into myotubes. Previous studies indicate that myogenic induction of the cyclin-dependent kinase inhibitor p21 results in an inhibition of apoptotic cell death in addit...

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Hlavní autoři: Fujio, Yasushi, Guo, Kun, Mano, Toshiaki, Mitsuuchi, Yasuhiro, Testa, Joseph R., Walsh, Kenneth
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84350/
https://ncbi.nlm.nih.gov/pubmed/10373556
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