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The Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription

The human UV-damaged-DNA binding protein DDB has been linked to the repair deficiency disease xeroderma pigmentosum group E (XP-E), because a subset of XP-E patients lack the damaged-DNA binding function of DDB. Moreover, the microinjection of purified DDB complements the repair deficiency in XP-E c...

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Udgivet i:Mol Cell Biol
Principais autores: Shiyanov, Pavel, Hayes, Steven A., Donepudi, Manjula, Nichols, Anne F., Linn, Stuart, Slagle, Betty L., Raychaudhuri, Pradip
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373543/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.4935
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