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Suppression of E1A-Mediated Transformation by the p50E4F Transcription Factor

The adenovirus E1A gene can act as an oncogene or a tumor suppressor, with the latter effect generally arising from the induction of apoptosis or the repression of genes that provide oncogenic growth stimuli (e.g., HER-2/c-erbB2/neu) or increased metastatic invasiveness (e.g., metalloproteases). In...

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Autores principales: Fernandes, Elma R., Rooney, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC84272/
https://ncbi.nlm.nih.gov/pubmed/10373523
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