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Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase

Mutagenized human 293 cells containing an interleukin-1 (IL-1)-regulated herpes thymidine kinase gene, selected in IL-1 and gancyclovir, have yielded many independent clones that are unresponsive to IL-1. The four clones analyzed here carry recessive mutations and represent three complementation gro...

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Detalhes bibliográficos
Main Authors: Li, Xiaoxia, Commane, Mairead, Burns, Carmel, Vithalani, Kalpa, Cao, Zhaodan, Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84262/
https://ncbi.nlm.nih.gov/pubmed/10373513
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