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Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins

Multiple adenovirus (Ad) early proteins have been shown to inhibit transcription activation by p53 and thereby to alter its normal biological functioning. Since these Ad proteins affect the activity of p53 via different mechanisms, we examined whether this inhibition is target gene specific. In addi...

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Bibliografiske detaljer
Main Authors: Steegenga, Wilma T., Shvarts, Avi, Riteco, Nicole, Bos, Johannes L., Jochemsen, Aart G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84246/
https://ncbi.nlm.nih.gov/pubmed/10207112
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