Oxidative Stress-Induced Destruction of the Yeast C-Type Cyclin Ume3p Requires Phosphatidylinositol-Specific Phospholipase C and the 26S Proteasome

The yeast UME3 (SRB11/SSN3) gene encodes a C-type cyclin that represses the transcription of the HSP70 family member SSA1. To relieve this repression, Ume3p is rapidly destroyed in cells exposed to elevated temperatures. This report demonstrates that Ume3p levels are also reduced in cultures subject...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Cooper, Katrina F., Mallory, Michael J., Strich, Randy
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84127/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3338
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