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Oxidative Stress-Induced Destruction of the Yeast C-Type Cyclin Ume3p Requires Phosphatidylinositol-Specific Phospholipase C and the 26S Proteasome

The yeast UME3 (SRB11/SSN3) gene encodes a C-type cyclin that represses the transcription of the HSP70 family member SSA1. To relieve this repression, Ume3p is rapidly destroyed in cells exposed to elevated temperatures. This report demonstrates that Ume3p levels are also reduced in cultures subject...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Cooper, Katrina F., Mallory, Michael J., Strich, Randy
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3338
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