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The C Terminus of Ku80 Activates the DNA-Dependent Protein Kinase Catalytic Subunit

Ku is a heterodimeric protein with double-stranded DNA end-binding activity that operates in the process of nonhomologous end joining. Ku is thought to target the DNA-dependent protein kinase (DNA-PK) complex to the DNA and, when DNA bound, can interact and activate the DNA-PK catalytic subunit (DNA...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Singleton, B. K., Torres-Arzayus, M. I., Rottinghaus, S. T., Taccioli, G. E., Jeggo, P. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3267
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