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Atm Is Dispensable for p53 Apoptosis and Tumor Suppression Triggered by Cell Cycle Dysfunction

Both p53 and ATM are checkpoint regulators with roles in genetic stabilization and cancer susceptibility. ATM appears to function in the same DNA damage checkpoint pathway as p53. However, ATM’s role in p53-dependent apoptosis and tumor suppression in response to cell cycle dysregulation is unknown....

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Autors principals: Liao, Mai-Jing, Yin, Chaoying, Barlow, Carrolee, Wynshaw-Boris, Anthony, van Dyke, Terry
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84103/
https://ncbi.nlm.nih.gov/pubmed/10082576
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