Atm Is Dispensable for p53 Apoptosis and Tumor Suppression Triggered by Cell Cycle Dysfunction

Both p53 and ATM are checkpoint regulators with roles in genetic stabilization and cancer susceptibility. ATM appears to function in the same DNA damage checkpoint pathway as p53. However, ATM’s role in p53-dependent apoptosis and tumor suppression in response to cell cycle dysregulation is unknown....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liao, Mai-Jing, Yin, Chaoying, Barlow, Carrolee, Wynshaw-Boris, Anthony, van Dyke, Terry
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1999
Gaiak:
Cell Growth and Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC84103/
https://ncbi.nlm.nih.gov/pubmed/10082576
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